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目的从临床和血液流变学方面探讨灯盏花素治疗急性脑梗死的效应及机理。方法本组78例急性脑梗死患者,随机分为灯盏花素治疗组和丹参对照组进行临床研究。结果灯盏花素组患者临床好转率明显高于丹参组,且治疗前后血液流变学指标明显好转。而丹参组无明显变化。结论灯盏花素具有改善微循环,抗血小板聚集,抗凝作用,能有效地治疗急性脑梗死。
Objective To investigate the effect and mechanism of breviscapine in the treatment of acute cerebral infarction from the aspects of clinical and hemorheology. Methods A total of 78 patients with acute cerebral infarction were randomly divided into breviscapine treatment group and Salvia miltiorrhiza control group for clinical study. Results Breviscapine group clinical improvement rate was significantly higher than Salvia group, and the treatment of blood rheology indicators improved significantly. The Salvia group no significant change. Conclusion Breviscapine can improve microcirculation, anti-platelet aggregation, anticoagulant effect, and can effectively treat acute cerebral infarction.