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目的 总结肝门部胆管癌诊断和治疗的经验。方法 回顾性分析经手术和病理证实的肝门部胆管癌 2 3例的临床特征、手术方法和随访结果。结果 2 3例中手术切除率为 39 1% (9/ 2 3) ,根治切除率为13 0 % (3/ 2 3) ,术后并发症发生率为 30 4 % (7/ 2 3) ,随访率为 6 9 6 % (16 / 2 3)。根治性切除 1、3、5年生存率分别为 10 0 % (3/ 3)、33 3% (1/ 3)、0 (0 / 3)。姑息性切除 1、1 5、2年生存率分别为 75 % (3/ 4 )、2 5 % (1/ 4 )、0(0 / 4 )。非切除者平均生存 15个月。结论 治疗应力争行根治性切除 ,对不能切除者尽量行姑息性引流及支持治疗 ,以延长生存期及提高生存质量。
Objective To summarize the experience of diagnosis and treatment of hilar cholangiocarcinoma. Methods The clinical features, surgical methods and follow-up results of 23 patients with hilar cholangiocarcinoma confirmed by surgery and pathology were retrospectively analyzed. Results The surgical resection rate was 39 1% (9/23) in 23 cases, radical resection rate was 13 0% (3/2 3), postoperative complication rate was 30 4% (7/2 3) The follow-up rate was 69.6% (16/23). The 1, 3, 5 year survival rates after radical resection were 10 0% (3/3), 33 3% (1/3) and 0 (0/3), respectively. The palliative resection rate of 1,1 5 year and 2 year survival rates were 75% (3/4), 25% (1/4) and 0 (0/4), respectively. Non-resected people live an average of 15 months. Conclusions The treatment of stress strives for a radical curative resection, as far as possible unresectable palliative drainage and supportive treatment to prolong survival and improve quality of life.