DDS治疗SLE的血小板减少症有效

• 作 者: 周云龙
• 出 处: 国外医学.皮肤病学分册
• 发表日期: 1990年02期
• 关键词: 玻璃体出血 病变复发 皮肤病变 炎性损害 关节病 实验检查 手指血 末梢 结合率 DNA

作者报告1例 SLE 的血小板减少症患者,经用DDS 治疗有效。患者女,29岁。1980年诊断为面部DLE,病史4年,此前曾有短暂的手指血管炎性损害和末梢关节病。实验检查:ANA 阳性(1:80),C_3、C_4降低,血小板计数140×10~9/L,DNA 结合率<20U/ml。其皮肤病变用 DDS 治疗,100mg/d 约2个月获良效。1年后皮肤病变复发,且血小板减少(11×10~9/L)。此前5个月曾患玻璃体出血,故重又使用 DDS,10天后血小板上升至67×10~9/L。

The authors report 1 patient with SLE with thrombocytopenia who is treated with DDS. Patient female, 29 years old. In 1980, the diagnosis of facial DLE, a history of 4 years, had had short-term vasculitis and peripheral vascular disease. Experimental test: ANA positive (1:80), C_3, C_4 decreased, platelet count 140 × 10 ~ 9 / L, DNA binding rate <20U / ml. The skin lesions with DDS treatment, 100mg / d about 2 months were good results. 1 year after the recurrence of skin lesions, and thrombocytopenia (11 × 10 ~ 9 / L). Prior to 5 months had vitreous hemorrhage, it re-use DDS, 10 days after the platelet increased to 67 × 10 ~ 9 / L.