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芥子气中毒和辐射损伤的机理相似,均对细胞DNA有特异的损害。它们作用机体后,各组织均可出现不同程度的损伤,其中细胞分裂旺盛的组织损伤更为严重。辐射损伤后小肠和造血组织有明显的损伤作用,但是致死剂量辐射损伤引起死亡的主要原因为造血功能的抑制,死亡时间在照射10天以后。当射线剂量超过了致死剂量(1000拉德以上)时,才出现因小肠损伤所导致的3～5天内死亡。可是芥子气则不同,1个致死剂量中毒后在3～5天内即可死亡,而且伴随出现一系列严重的肠道症状。看来,两种组织(骨髓、小肠)对两种损伤(芥子气与射线)因素的敏感性是有所不同
The mechanisms of mustard gas poisoning and radiation damage are similar, all of which have specific damage to cellular DNA. After they are applied to the body, all the tissues can have different degrees of damage, among which the cell division with strong cell division is more serious. Radiation injury in the small intestine and hematopoietic tissue have obvious damage, but the main cause of death caused by lethal dose radiation injury is the inhibition of hematopoietic function, the death time after irradiation for 10 days. When the radiation dose exceeds the lethal dose (1000 rad or more), the small intestine injury occurs within 3 to 5 days of death. But mustard gas is different, a lethal dose poisoning in 3 to 5 days to die, but accompanied by a series of serious intestinal symptoms. It appears that the two tissues (bone marrow, small intestine) are somewhat different in sensitivity to both injury (mustard and rays)