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四氧嘧啶性糖尿病与自由基反应四氧密啶致糖尿病的作用机制学说较多。1984年,Sandler等的研究曾证明,尼克酰胺和四氧嘧啶并用时具有保持细胞内NAD(H)浓度的作用,而不影响细胞内氧消耗和胰岛素分泌与合成,但能增加谷酰胺的呼吸作用。由此推测四氧嘧啶...
Alloxan-induced diabetes mellitus and free radical reaction of ox-pyrimidine-induced diabetes more mechanism. In 1984, Sandler and other studies have shown that nicotinamide and alloxan used in combination with the role of maintaining intracellular NAD (H) concentration, without affecting intracellular oxygen consumption and insulin secretion and synthesis, but can increase the glutamine breathing effect. From this speculation alloxan ...