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乳腺癌是女性最常见的恶性肿瘤之一,乳腺癌的病因,发病机制迄今尚未完全明确。肿瘤的基因发生学说成为研究热点。研究女性乳腺癌发病风险与基因多态性的相关性,同时采取相应的干预措施,可以一定程度降低女性乳腺癌的发病率。本文就XRCC1基因多态性与乳腺癌易感性的研究进展作一综述。
Breast cancer is one of the most common malignant tumors in women. The etiology and pathogenesis of breast cancer have not yet been completely elucidated. The genesis of tumors has become a hot research topic. To study the correlation between the risk of breast cancer and genetic polymorphism in women and to take corresponding interventions may reduce the incidence of breast cancer in women to some extent. This article reviews the research progress of XRCC1 gene polymorphism and breast cancer susceptibility.