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在深部铜绿假单胞菌感染引起的肾脓肿鼠模型中使用克林沙星(剂量50mg/kg,每日2次,连续给药5d),使细菌计数下降了 4个数量级,在所测定的肾脏中细菌完全清除率为88%.
Clinofloxacin (50 mg / kg, twice daily, 5 consecutive days) was used in a murine model of renal abscess caused by deep P. aeruginosa infection to reduce the bacterial count by 4 orders of magnitude in the kidneys tested The total bacterial clearance rate was 88%.