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It is universally recognized that excessive depletion of fluid from the circulation after severe burn injury result in burn shock.This initial hypovolemic phase is a potentially fatal condition coincides with early death and serves as a predisposing cause of many life-threatening complications such as tissue edema and multiple organ dysfunctions (MODS).Prompt and sufficient fluid resuscitation as early as possible is widely used to restore effective intravascular volume and improve organ perfusion as the standard treatment regime for this hypovolemic phase post severe burn injury.Unfortunately,conventional fluid resuscitation is inevitable delayed and even impossible when mass victims occur in austere environments such as battlefield,earthquake,or accidents.In such circumstance,severe burn injury is associated with high mortality for the lack of sufficient medical support.At present,oral fluid resuscitation and HDACI in early period of burn shock are important measures in the treatment of casualties in the battlefield as well as in mass casualties in lieu of the means of establishing a venous line.