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如何控制肾病综合征的并发症及复发成为儿科医师研究的课题,本文对86例肾病综合征患儿的临床及治疗结果进行分析,以便寻找新的有效治疗方案。 临床资料 我院1988年至1996年8年间住院治疗肾病综合征患儿86例,男78例,女8例;年龄10个月~12岁;首次发病59例,反复、复发27例。入院时临床表现及实验室检查;高度浮肿72例,一般浮肿14例;尿蛋白量2~4g/d 58例,>4g/d 28例;血白蛋白15~30g/L 61例,<15g/L 25例;血胆固醇5.6~12.9mmol/L 56例,>12.9mmol/L 30例;凝血酶原时间缩短72例;血纤维蛋白原4~6g/L 66例,>6g/L 20例;OT试验(-)52例(60%),PHA试验(-)43例(50%)。治疗随机分成3个组。对照组采用强的松,开始剂
How to control the complications and recurrence of nephrotic syndrome as a pediatrician’s research topic, the 86 cases of nephrotic syndrome in children with clinical and treatment results were analyzed in order to find a new and effective treatment options. Clinical data Our hospital from 1988 to 1996, 8 years hospitalized children with nephrotic syndrome in 86 cases, 78 males and 8 females; aged 10 months to 12 years; 59 cases of the first incidence, repeated and recurrent in 27 cases. Clinical manifestations at admission and laboratory tests; 72 cases of high edema, general edema in 14 cases; urinary protein 2 ~ 4g / d 58 cases,> 4g / d 28 cases; serum albumin 15 ~ 30g / / L 25 cases; blood cholesterol 5.6 ~ 12.9mmol / L 56 cases,> 12.9mmol / L 30 cases; prothrombin time shortened 72 cases; fibrinogen 4 ~ 6g / L 66 cases,> 6g / L 20 cases ; OT test (-) 52 cases (60%), PHA test (-) 43 cases (50%). The treatment was randomly divided into three groups. The control group used prednisone, start agent