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本文就结扎家兔左前降支造成实验性急性心肌梗塞模型,以心电图标准Ⅱ导联的ST段明显抬高及血清SGOT升高作为心肌梗塞形成的指标,用N-BT染色法测定梗塞范围。观察丹参、小紫丹参、丹参素及丹参酮Ⅱ-A磺酸钠等注射液对心肌梗塞的影响,并与心得安作比较,结果发现四种丹参注射液均能明显缩小心梗范围,与心得安比较,无显著差异,其中小紫丹参注射液疗效较好。
In this paper, the model of experimental acute myocardial infarction caused by ligating the left anterior descending artery in rabbits was used. The ST segment elevation and serum SGOT elevation in ECG standard II lead were used as indicators of myocardial infarction. The extent of infarction was determined by N-BT staining. Observed the effects of Danshen, Xiaozi Salvia, Danshensu and sodium tanshinone II-A sulphonate injections on myocardial infarction, and compared with propranolol. The results showed that four Salvia miltiorrhiza injections can significantly reduce the scope of infarct, and experience There was no significant difference between the two groups. Among them, Xiao Zi Dan Shen Injection had better efficacy.