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眼表瘢痕性疾病可以由物理及化学损伤、手术、感染、免疫性眼皮肤粘膜异常、药物和各种系统疾病引起。它可以导致眼睑位置异常、干眼症以及角膜病变 ,严重者造成视力损害。眼表瘢痕性疾病的诊断依靠仔细询问病史、对患者全面体检和多种辅助检查 ,重点是寻找病因及对病情评价。治疗应全面兼顾药物治疗和手术治疗。药物治疗以抑制外源性刺激物、治疗干眼症、抗感染和免疫抑制为目的 ,针对不同的病因和病情进行选择 ;外科手术主要是纠正倒睫及眼睑位置异常、治疗干眼症 ,进行结膜移植、粘膜移植、角膜缘干细胞移植、羊膜移植、角膜移植手术重建眼表功能 ,对于并发白内障或继发青光眼的患者也应同时采取相应处理。
Ocular cicatricial disease can be caused by physical and chemical damage, surgery, infections, immunodeficiency, ocular mucosal abnormalities, drugs and various systemic diseases. It can cause abnormal eyelid position, dry eye and corneal disease, severe visual impairment. Ocular cicatricial disease diagnosis depends on careful history, comprehensive physical examination and a variety of auxiliary examination, the focus is to find the cause and evaluation of the disease. Treatment should take into account both drug treatment and surgical treatment. Drug therapy to inhibit exogenous stimuli, the treatment of dry eye, anti-infective and immunosuppressive purposes for different etiologies and conditions to choose; surgery is mainly to correct the trichiasis and eyelid position abnormalities, the treatment of dry eye disease, Conjunctival transplantation, mucosal transplantation, limbal stem cell transplantation, amniotic membrane transplantation, corneal transplant surgery reconstruction ocular surface function, for patients with concurrent cataracts or secondary glaucoma should also take appropriate treatment.