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目的:探讨急性有机磷农药中毒患者接受长托宁治疗的临床疗效。方法:选择2012年1月—2016年1月期间在我院接受治疗的急性有机磷农药中毒患者90例为研究对象,将其按照中毒程度随机均分为两组,对照组采用阿托品联合氯磷定治疗,观察组应用长托宁联合氯磷定治疗,比较两组患者的临床疗效。结果:观察组患者的治愈率95.6%,远超过对照组的84.4%;观察组患者的中毒症状消失时间、血胆碱酯酶恢复时间、住院时间、呼吸衰竭发生率、中间综合征发生率和不良反应发生率均显著低于对照组;两组比较具有统计学意义(P<0.05)。结论:长托宁应用于急性有机磷农药中毒的治疗取得了良好的临床疗效,大幅度提升了治愈率,显著改善了患者的中毒症状,使用安全,发生的不良反应较少,值得大力推广。
Objective: To investigate the clinical efficacy of penehyclidine hydrochloride in patients with acute organophosphorus pesticide poisoning. Methods: Ninety patients with acute organophosphorus pesticide poisoning who were treated in our hospital from January 2012 to January 2016 were selected and divided into two groups according to the degree of poisoning. The control group was treated with atropine combined with chlorophosphorus Given the treatment, the observation group was treated with penehyclidine and chlorophyll, and the clinical efficacy was compared between the two groups. Results: The cure rate of the observation group was 95.6%, far exceeding 84.4% of the control group. The disappearance time of the poisoning symptom, the recovery time of the blood cholinesterase, the length of hospital stay, the incidence of respiratory failure, the incidence of intermediate syndrome, Adverse reactions were significantly lower than the control group; two groups was statistically significant (P <0.05). Conclusion: The application of penehyclidine in acute organophosphorus pesticide poisoning has achieved good clinical curative effect, greatly improved the cure rate, significantly improved the patient’s symptoms of poisoning, safe use, fewer adverse reactions, it is worth to promote.