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米非司酮配伍前列腺素类药物终止早孕最低有效剂量的研究,充分利用现有妇幼保健三级网资源,在区、县级妇幼保健医疗机构对1003例要求终止妊娠的妇女(停经≤49天),采用流行病学临床序贯试验方法,随机分成3组。组间对比流产效果成功率分别为92.0％、89.8％、92.4％,不完全流产率分别为3.1％、2.5％、1.4％,失败率为4.9％、7.7％、6.2％,流产效果比较,无显著性差异(P>0.05)。结果证实,以最低剂量米非司酮100mg配伍前列腺素同样能取得满意的终止早孕效果。
Mifepristone combined with prostaglandin drugs to terminate the minimum effective dose of early pregnancy research, make full use of existing maternal and child health tertiary network resources, district and county MCH health care of 1003 women who require termination of pregnancy (menopause ≤ 49 days ), Using epidemiological clinical sequential test method, were randomly divided into three groups. The success rates of comparison abortion were 92.0%, 89.8%, 92.4% respectively. The rates of incomplete abortion were 3.1%, 2.5% and 1.4% respectively. The failure rates were 4.9%, 7.7% and 6.2% Significant difference (P> 0.05). The results confirmed that the lowest dose of mifepristone 100mg compatibility prostaglandin also be able to obtain satisfactory termination of early pregnancy effect.