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目的对氨甲蝶呤和天花粉保守治疗剖宫产瘢痕妊娠的疗效及安全性进行评价;方法资料选自2010年2月-2013年2月在我院救治的剖宫产瘢痕妊娠18例,所有患者均予以氨甲蝶呤和天花粉保守治疗,分析患者的临床疗效和不良反应的情况。结果所有患者经治疗后,血绒毛膜促性腺激素水平恢复正常;所有患者均不同程度的存在全身酸痛、发热,以及臀部的注射部位存在疼痛和红肿等不良反应,未出现过敏性休克和呼吸困难等重症不良反应。结论剖宫产瘢痕妊娠应尽早的进行超声诊断,并予以氨甲蝶呤和天花粉保守治疗,可具有较好的疗效,并且不良反应的发生率低,安全性好,疗效显著。
Objective To evaluate the efficacy and safety of conservative treatment of methotrexate and TCS in the treatment of cesarean scar pregnancy.Methods Data were selected from 18 cases of cesarean scar pregnancy treated in our hospital from February 2010 to February 2013. All Patients were treated with methotrexate and TCS conservative treatment of patients with clinical efficacy and adverse reactions. Results All patients returned to normal levels of serum human chorionic gonadotropin after treatment. All patients suffered from body aches, fever and pain and swelling at the injection site of the buttocks to varying extents without any episodes of anaphylactic shock and dyspnea Other serious adverse reactions. Conclusions Cesarean scar pregnancy should be diagnosed as soon as possible by ultrasound and treated conservatively with methotrexate and TCS, which has good curative effect, low incidence of adverse reactions, good safety and significant curative effect.