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Liver cirrhosis is the terminal stage caused by various chronic liver injury. There are many complications and death in the late stage. There is no effective treatment method at present. In recent years, with the rapid development of regenerative medicine, the treatment of liver cirrhosis based on stem cell transplantation technology has become a new research hotspot. Scholars at home and abroad have carried out a series of basic and clinical research, and achieved certain results, which brings new hope for the majority of patients with liver cirrhosis. This article reviews the research progress of various types of stem cells in the treatment of liver cirrhosis.