【摘 要】
：
Diabetic kidney disease has now become the leading cause of end-stage renal disease. Podocytes are an important filtration barrier of the glomerulus, and their damage plays an important role in the occurrence and progression of glomerular sclerosis and DK
【机 构】
：
Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Affiliated Hospital of Shando
论文部分内容阅读
Diabetic kidney disease has now become the leading cause of end-stage renal disease. Podocytes are an important filtration barrier of the glomerulus, and their damage plays an important role in the occurrence and progression of glomerular sclerosis and DKD. This article discusses the molecular mechanism of traditional Chinese medicine on the protection of podocyte damage in diabetic kidney disease from the aspects of anti-oxidative stress, activating autophagy, and regulating signal pathways, in order to further deepen the modern material basis theory of traditional Chinese medicine treatment and provide reference for the treatment of DKD.
其他文献
新型冠状病毒肺炎疫情稳定以来,医院门诊就诊患者逐渐恢复常态,接受心电图相关检查的患者数量也不断增加.虽然心电图相关检查感染严重急性呼吸综合征冠状病毒-2(SARS-CoV-2)的风险较低,但是对新型冠状病毒肺炎的防控仍然不能掉以轻心.在临床工作中必须遵循标准操作流程和感染防控方案进行操作.本文通过总结针对新型冠状病毒肺炎的防控措施,根据不同心电图检查感染SARS-CoV-2的风险特点,从患者管理、医务人员防护、清洁消毒等方面制定感染防控方案,防止医院内交叉感染的发生,保障患者与医务人员安全.
Objective: To prepare the liposomes of mangrove oil, Optimization of the formulation of mangrove oil liposomes by Box Behnken response surface methodology.Methods: Preparation of Rhododendron oil liposomes by ethanol injection probe ultrasound, Determinat
Objective: To investigate whether The small nuclear RNA activating complex polypeptide 3 (SNAPC3) gene rs12093 polymorphism is associated with ischemic stroke (IS) and Traditional Chinese Medicine (TCM) syndromes of IS. Methods: This study enrolled 774 pa
Objective: To investigate the effect of Fufei Gushen Decoction on airway inflammation and glucocorticoid receptor in rats with chronic obstructive pulmonary disease. Methods: Fifty Wistar male rats were randomly divided into 5 groups: blank control group,
Objective: To investigate the relationship between platelet-lymphocyte ratio (PLR) and carotid atherosclerosis (CAS) in middle-aged and elderly patients with T2DM. Methods: A total of 420 middle-aged and elderly patients with T2DM who were hospitalized in
Objective: To explore the rules of acupuncture point selection in thetreatment of rheumatoid arthritis by applying data mining and modern Statistical software.Methods: We retrieved literature from China hownet(CNKI), VIP database(VIP), Wanfang,PubMed, MED
Objective: To explore the effect of TRAF6 gene silencing on the function of hepatocellular carcinoma SMCC7721 and its possible mechanism. Method: Cell lines were constructed by cell transfection technology and verified by quantitative real-time PCR. Cell
Objective: To study the potential therapeutic effect of Yigan Powder on Alzheimer\'s disease (AD) comorbid Depressive Disorder with Network Pharmacology. Methods: The active ingredients of Yigan Powder were screened from Traditional Chinese Medicine Sys
Objective: The differences of ovarian morphology, reproductive hormones, glucose and lipid metabolism and intestinal bacteria in rats with polycystic ovary syndrome (PCOS) induced by triazole were compared. Method: Eighteen 21 SPF female SD rats were rand
Objective: To systematically evaluate the effect of Yiqi Wenyang Huoxue therapy in treating diabetic kidney disease(DKD) of stage Ⅲ-Ⅳ. Method: The relevant literature was retrieved by computer from CNKI, Wanfang and VIP databases,CBM,PubMed,EMBase,Cochra