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目的探讨米索前列醇（米索）在预防产后出血中的作用。方法米索组100例，在胎儿前肩娩出后立即给予米索200μg口服．接产处理完毕后再给予米索200μg肛塞。催产素组100例。在胎儿前肩娩出后立即给予催产素20u肌注。观察两组用药后第三产程时间，产后2小时出血量及产后出血发生率。结果两组产后2小时出血量有显著性差异，米索组优于催产素组；第三产程时间，产后出血发生率等无显著性差异。结论米索前列醇副作用少，给药方便，用药途径广．价格低廉．不需低温保存，对子宫平滑肌的收缩作用较催产素强．预防产后出血作用肯定．值得临床推广应用。
Objective To investigate the role of misoprostol (misoprostol) in preventing postpartum hemorrhage. Methods 100 cases of misoprostol were given orally 200μg of misoprostol immediately after the delivery of the fetus’s anterior shoulder. Follow-up treatment and then given misoprostol 200μg anal plug. Oxytocin group of 100 cases. Immediate oxytocin 20u intramuscular injection immediately after the anterior shoulder was delivered. The duration of the third stage of labor, the amount of bleeding after 2 hours and the incidence of postpartum hemorrhage were observed after treatment. Results The two groups of postpartum hemorrhage 2 hours were significantly different, misoprostol group was better than oxytocin group; the third stage of labor, the incidence of postpartum hemorrhage no significant difference. Conclusion Misoprostol has few side effects, convenient administration and wide application. Low price. Without cryogenic preservation, contraction of uterine smooth muscle stronger than oxytocin. Preventive effect of postpartum hemorrhage certainly. Worthy of clinical application.