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本文采用敏感性高,特异性强和重复性好的S-2251底物显色法对37例放置金属单环后月经量过多、经量正常和未放器经量正常妇女的子宫内膜进行t-PA活性测定。结果表明放器后经量过多者子宫内膜组织纤溶酶原激活物(t-PA)活性明显高于放器后经量正常和未放器者,但后两组之间的差别在统计学上无显著性意义。带器妇女的经量与t-PA活性之间存在正相关性。本文提示,只有放器后经量增多者子宫内膜t-PA活性才增加;虽放器但经量正常者,其t-PA活性并不增加。
In this paper, the sensitivity, specificity and repeatability of S-2251 substrate chromogenic method 37 cases placed metal ring after menorrhagia, normal menstruation and normal women’s endometrium T-PA activity was measured. The results showed that the endometrial tissue plasminogen activator (t-PA) activity was significantly higher than that after the device was overloaded, but the difference between the latter two groups was Statistically no significant significance. There was a positive correlation between menstrual flow and t-PA activity. This article suggests that only by the increase in endometrial volume after endometrial t-PA activity was increased; although the device but the normal amount of t-PA activity did not increase.