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我科在应用卡托普利治疗高血压病的过程中,出现剧烈干咳5例,现报告如下。 1 病例报告例1 男,54岁。因“脑血栓形成”急性期、“高血压病”Ⅲ期入院。给予卡托普利25mg/次,3次/d。服药后第5天起出现阵发性干咳,逐渐加剧,夜间更甚,影响睡眠。血象、胸片、喉镜等均未见异常,服多种止咳祛痰药及止咳片无效。后考虑与卡托普利有关,遂停药,症状明显好转。2天后干咳消失。再服药又引起干咳,停药1天后咳嗽又见消失。例2,女,55岁。因“高血压病”Ⅲ期入院,给予卡托普利25mg/次,3次/d治疗。服药2天后出现干咳,1月后干咳加剧,呈阵发性,夜间更甚。血象及胸
Our department in the application of captopril treatment of hypertension in the course of severe cough in 5 cases, are as follows. 1 case report 1 male, 54 years old. Due to the “cerebral thrombosis” acute phase, “hypertension” Ⅲ hospitalization. Give captopril 25mg / time, 3 times / d. Occurred on the 5th day after taking paroxysmal dry cough, gradually aggravated, even more at night, affecting sleep. Blood, chest X-ray, laryngoscope, etc. were no abnormalities, taking a variety of cough expectorants and cough tablets ineffective. After considering the captopril related, then withdrawal, the symptoms were significantly improved. 2 days after the dry cough disappeared. Then medication and cause dry cough, cough disappeared after stopping 1 day. Example 2, female, 55 years old. Because of “Hypertension” Ⅲ hospitalization, given captopril 25mg / time, 3 times / d treatment. 2 days after taking dry cough, dry cough intensified in January, was paroxysmal, even more night. Blood and chest