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P５３基因是与人类相关性最高的抑癌基因之一，其P５３蛋白能抑制细胞增殖和诱导细胞凋亡。细胞间黏附分子－１（intercellularadhesionmolecullar－１，ICAM－１）是淋巴细胞相关抗原－１（LFA－１）的配体，协助T细胞识别抗原呈递细胞所呈递的抗原，激活淋巴细胞和吞噬细胞，
P53 gene is one of the most human tumor suppressor genes, and its P53 protein can inhibit cell proliferation and induce apoptosis. Intercellular adhesion molecule-1 (ICAM-1), a ligand for lymphocyte-associated antigen-1 (LFA-1), assists T cells in recognizing antigen presented by antigen-presenting cells and activating lymphocytes and phagocytes,