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小儿播散性曲菌病和毛霉菌病较少见,但常常累及全身多脏器,往往引起患儿死亡,且没有特异临床症状,生前往往得不到正确诊断。本文所报二例均经尸检证实,报告如下: 例1 女 9岁住院号104495 发热近3个月,手足关节肿胀,伴头痛,有时呕吐。当地医院按“感冒”、“风湿热”用抗菌素、激素治疗,病情稍有好转,但仍发热,逐渐消瘦。入院前一个月拍胸片示:肺内中带有点状影。化验:白细胞1.5-3万,分类在正常范围。继续消炎、对症治疗一个月,肺炎好转,突然抽搐。以“抽搐待查”住院。查体:T38.4 P160,神志清,贫血外貌,皮肤有散在出血点。双眼凝视、瞳孔等大,对光反应迟
Pediatric disseminated aspergillosis and mucormycosis are rare, but often involve multiple body organs, often cause death in children, and no specific clinical symptoms, often can not be correctly diagnosed during their lifetime. The two reported cases were confirmed by autopsy, the report is as follows: Example 1 female 9-year-old hospitalization 104495 fever nearly 3 months, swollen hands and feet, with headache, and sometimes vomiting. The local hospital by “cold”, “rheumatic fever” with antibiotics, hormone therapy, the condition was slightly better, but still fever, weight loss. A month before admission to take chest radiograph showed: with a shadow in the lungs. Laboratory: WBC 15,000, classified in the normal range. Continue to anti-inflammatory, symptomatic treatment for a month, pneumonia improved, suddenly convulsions. To “convulsions pending investigation” hospitalization. Physical examination: T38.4 P160, clear consciousness, anemia appearance, scattered in the skin bleeding point. Eyes staring, pupils and other large, light response late