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作者对家族性甲状腺髓样癌(MTC)患者和正常人进食后刺激胃泌素分泌的情况作比较研究,旨在进一步研究降钙素与胃泌素释放间的关系。研究对象为15例经组织学检查确诊的 MTC 患者和10名正常对照者。MTC 组为家族有Ⅱ型多腺性内分泌肿瘤的患者。依据血浆降钙素水平将受试者分为以下3组:第Ⅰ组 MTC 11例,于研究时血浆降钙素基础值和/或峰值(用钙剂或五肽胃泌素刺激)异常,其中例1～3已行甲状腺切除术,然其降钙素水乎仍增高提示 MTC 残留,例4～11在研究时尚未行颈部手术探查与甲状腺切除术,其中例4、7、11于研究
The authors compared familial medullary thyroid carcinoma (MTC) patients and healthy subjects to stimulate the secretion of gastrin after a comparative study to further investigate the relationship between calcitonin and gastrin release. The subjects were 15 patients with histologically confirmed MTC and 10 normal controls. MTC group is a family of patients with type Ⅱ polyglandular endocrine tumors. Subjects were divided into the following three groups based on plasma calcitonin levels: Group I, MTC, in 11 cases, abnormalities of plasma calcitonin base and / or peak (stimulated with calcium or pentagastrin) at the time of study, Of which cases 1 to 3 have been undergone thyroidectomy, while the calcitonin water is still high, suggesting that residual MTC, cases 4 to 11 in the study has not yet underwent neck surgery and thyroidectomy, of which 4,7,11 the study