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目的 了解前白蛋白 (PA)作为白血病对肝浸润的意义。方法 33例患儿在治前与其中完全缓解后的 2 4例患儿 ,和 30例健康儿童对照组 ,通过免疫比浊法测定PA ,并检测其它肝功能值。结果 33例治前患儿 ,11例PA下降 (与对照组PA相比 ,t检验P <0 .0 1) ,3例白蛋白降低 ,3例谷丙转氨酶、9例谷草转氨酶升高 ,1例总胆红素升高 ,治前PA异常的例数高于肝功能其它值异常的例数。其中经治疗完全缓解后的 2 4例患儿 ,PA及肝功能其它值则均在正常范围。结论 通过PA的检测 ,发现治前白血病对肝浸润时 ,PA的变化较肝功能其它值的变化为明显
Objective To understand the significance of prealbumin (PA) as leukemia on liver infiltration. Methods Thirty-three infants were randomly divided into control group (n = 24) and control group (n = 30). The levels of PA were determined by immunoturbidimetry and other liver function values were measured. Results 33 cases of pre-treatment children, 11 cases of PA decreased (compared with the control group PA t test P <0.01), 3 cases of albumin decreased, 3 cases of alanine aminotransferase, 9 cases of aspartate aminotransferase increased, 1 Cases such as elevated total bilirubin, PA abnormalities before treatment than the number of other cases of abnormal liver function number. Among them, 24 cases of complete remission after treatment, PA and other liver function values were in the normal range. Conclusion Through the detection of PA, it is found that when the pre-treatment leukemia infiltrates the liver, the change of PA is more obvious than other values of liver function