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Objective:To compare the therapeutic effects of Shengjing Zhongzi Tang (生精种子汤 Decoction for Generating Sperms) and Wuzi Yanzong Wan (五子衍宗 丸 Pills for Reproduction) for asthenospermia and oligozoospermia.Methods:Seventy patients with asthenospermia and oligozoospermia were divided into a treatment group of 35 cases treated with Shengjing Zhongzi Tang and a control group of 35 cases treated with Wuzi Yanzong Wan for 3 months respectively.The therapeutic effects were evaluated,the semen parameters were analyzed and the spermatic morphology was judged before and after treatment.Results:In the treatment group,the total effective rate was 91.4％ with a pregnant rate of 8.6％ spouses,and the markedly effective rate was 65.7％.In the control group,the total effective rate was 85.7％ with a pregnant rate of 5.7％ spouses,and the markedly effective rate was 54.3％.Both the total effective rate and the markedly effective rate were higher in the treatment group than those in the control group,but with no significant statistical difference (P＞0.05).The spermatic density,spermatic motility and the percentage of normal spermatic morphology were obviously enhanced in the two groups with the indexes in the treatment group superior to those in the control group (P＜0.05 or P＜0.01).Conclusion:Shengjing Zhongzi Tang with obvious therapeutic effects for asthenospermia and oligozoospermia can significantly enhance the spermatic density and motility,and raise the pregnant rate in spouses.