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本文报道了25例肝肺包虫病患者经吡喹酮治疗后肺包虫变化的临床和实验室观察结果。经吡喹酮治疗后未行包虫囊摘除术的22例患者中,14例肺包虫囊肿消失或部分消失,8例肺包虫囊肿缩小或稳定。2例近期手术者,原头蚴死亡率计数分别为68％和89％,包虫囊壁组织学检查未见到生发层。2例治疗后1年手术者,原头蝴死亡率为100％,包虫囊壁组织学检查无生发层,角质层也受到了明显的损害。结果表明,吡喹酮对肺包虫具有肯定的治疗作用,结合外科手术,临床治疗效果将会更好。
This article reports the clinical and laboratory observations of 25 patients with hepatobiliary hydatid disease after praziquantel treatment of pulmonary hydatid. Among the 22 patients who did not undergo hydatid cyst removal after praziquantel treatment, 14 cases of hydatid cyst disappeared or disappeared partially, and 8 cases of hydatid cyst contracted or stabilized. Two cases of recent surgery, the original cercariae mortality rates were 68% and 89%, hydatid cyst examination showed no germinal layer. After 2 years of operation, the death rate of the primary cranial fossa was 100%. There was no germinal layer in the hydatid cyst and the stratum corneum was also significantly damaged. The results showed that praziquantel has a positive therapeutic effect on pulmonary hydatid, and combined with surgery, the clinical treatment effect will be better.