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肿瘤是严重危害人类生命健康的重大疾病。在肿瘤研究中,干细胞研究加深了对肿瘤发生、发展的认识,提出了肿瘤来源于干细胞、肿瘤中存在肿瘤干细胞(cancerstemcell)的该学说认为,肿瘤组织中存在极少量瘤细胞,在肿瘤中充当干细胞的角色,具有无限增生的潜能,在启动肿瘤形成和生长中起着决定性的作用,而其余的大多数细胞,经过短暂的分化,最终死亡。因此只有采用靶向消灭肿瘤干细胞的策略,才能从根本上治愈肿瘤。
Tumor is a serious disease that seriously endangers human life and health. In cancer research, stem cell research has deepened the understanding of tumorigenesis and development, proposed that the tumor originated from stem cells, and there is cancer stem cells in the tumor. According to this theory, there are a few tumor cells in the tumor tissue, The role of stem cells, with the potential to proliferate indefinitely, plays a decisive role in initiating tumor formation and growth, while the majority of the remaining cells, after a brief period of differentiation, eventually die. Therefore, the strategy of eliminating cancer stem cells can only fundamentally cure the tumor.