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L_4过滤膜是一种纤维性聚酯膜,能吸附通过其血液中99.9%以上的白细胞,但能让红细胞和血小板自由通过。美国食品药物管理局(FDA)承认该膜用于输血和从人血清中分离白细胞。现使用L_4过滤膜处理精液,并且与上游法处理后的精液在精液质量和精子受精能力方面进行比较。手淫法获得30例精液标本(19例采自可疑不育病人,11例采自已生育的供精者),用来研究经精子洗涤和上游法与L_4膜过滤法处理后精液质量的不同,其中的17例(11例可疑不育病人,6例已生育的供精者)用来评估经上述两种制备方法处理后精子受精
L_4 filter membrane is a fibrous polyester membrane that can adsorb more than 99.9% of the white blood cells through its blood, but allows free passage of red blood cells and platelets. The U.S. Food and Drug Administration (FDA) admits the membrane is used to transfuse blood and isolate white blood cells from human serum. The semen is now treated with the L_4 filter and compared with the semen processed by the upstream method for semen quality and sperm fertility. Semen samples were obtained from masturbation (Semen 19 from suspicious infertile patients and 11 from self-fertilized donors) to study the differences in semen quality after sperm washing and upstream and L 4 membrane filtration Of 17 patients (11 suspicious infertile patients and 6 fertile donors) were used to assess sperm fertilization after the above two preparation methods