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目的探讨大鼠肝癌血供的影像表现。方法对１２只大鼠肝癌模型进行彩色多普勒血流显像（ＣＤＦＩ）、肝动脉造影（ＨＡ）以及门静脉造影（ＨＰ）检查并与病理对照。结果２～３ｍｍ瘤结节多为门脉单一血供（Ⅰ型），细胞分化较高；３～５ｍｍ瘤结节多为肝动脉和门脉双重血供（Ⅱ型），细胞分化较高；＞５ｍｍ瘤结节主要为肝动脉血供，门脉仅在瘤周参与血供（Ⅲ型），细胞分化较差。ＣＤＦＩ在瘤结节周边及内部显示的血流代表了造影所见的肿瘤血管和（或）肿瘤染色。结论大鼠肝癌血供演变的影像表现对人类肝癌诊断、介入治疗途径选择以及疗效预测具有参考意义。
Objective To investigate the imaging features of rat liver cancer blood supply. Methods Twelve rat liver cancer models were examined by color Doppler flow imaging (CDFI), hepatic arteriography (HA), and portal venography (HP) and compared with pathology. Results 2～3mm tumor nodules were mostly portal venous blood supply (type I), and the cell differentiation was high. The 3～5mm tumor nodules were mostly hepatic arterial and portal vein dual blood supply (type II) with high cell differentiation. >5mm tumor nodules are mainly hepatic arterial blood supply, portal veins are only involved in blood supply (type III) at the periphery of the tumor and cell differentiation is poor. The blood flow shown by CDFI around and inside the tumor nodules represents the tumor vessel and/or tumor staining seen by the angiography. Conclusion The imaging performance of rat liver cancer blood supply evolution has a reference significance for the diagnosis of human liver cancer, the choice of interventional therapy and the prediction of efficacy.