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阐述大肠癌nm23－H1的表达与淋巴结转移的关系。用免疫组化方法研究93例大肠癌中nm23－H1蛋白的表达。结呆发现nm23－H1蛋白低表达与淋巴结或远处转移显著相关（P＜0．05）；nm23－H1蛋白低表达预测大肠癌转移的灵敏性为90．5％，特异性为80．4％。表明检测nm23－H1蛋白可以预测大肠癌淋巴结或远处转移，从而可能成为临床治疗的判断依据。
Explain the relationship between the expression of nm23-H1 and lymph node metastasis in colorectal cancer. Immunohistochemistry was used to study the expression of nm23-H1 protein in 93 cases of colorectal cancer. The low expression of nm23-H1 protein was significantly associated with lymph node or distant metastasis (P<0.05). The low expression of nm23-H1 protein was predictive of the sensitivity of 90.5% for colorectal cancer metastasis, and the specificity was 80.4. %. It shows that the detection of nm23-H1 protein can predict the lymph node or distant metastasis of colorectal cancer, which may become the basis for the judgment of clinical treatment.