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人乳头状瘤病毒(HPV)是一类双链环状DNA病毒,具有高度组织特异性和宿主特异性,至今尚不能在体外培养,又无合适的实验动物,因而对其检测主要依赖于形态学方法和分子生物学技术。无论用何种检测方法,HPV表达概率受很多因素,如年龄、月经周期、外源性激素应用及宿主免疫潜能的影响,例如正常年轻女性使用口服避孕药者、怀孕、免疫抑制患者HPV检出率也较高。本文仅就近年来关于其检测方法的研究综述如下。
Human papillomavirus (HPV) is a type of double-stranded circular DNA virus that is highly tissue-specific and host-specific and has not yet been cultured in vitro and has not been adequately tested in laboratory animals, so its detection is largely dependent on morphology Methodology and molecular biology techniques. Regardless of the test used, the probability of HPV expression is affected by many factors, such as age, menstrual cycle, exogenous hormonal use, and host immune potential, such as the use of oral contraceptives in normal young women, pregnancy, and HPV detection in immunosuppressed patients Also higher. This article only in recent years on its detection methods are summarized below.