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目的观察更昔洛韦与纳洛酮联合应用治疗病毒性脑炎的临床疗效。方法将60例病毒性脑炎患者随机分为更昔洛韦纳洛酮组(治疗组)和更昔洛韦组(对照组),每组30例,两组患者都采用静脉给药,对两组患者治疗效果进行观察。结果更昔洛韦纳洛酮组治疗小儿病毒性脑炎,头痛、呕吐、抽搐、意识恢复的时间明显较更昔洛韦组缩短,两者比较差异有统计学意义(P<0.01)。结论更昔洛韦与纳洛酮联合应用治疗病毒性脑炎疗效显著,作用迅速、安全性好,不良反应少,值得临床推广。
Objective To observe the clinical efficacy of ganciclovir combined with naloxone in the treatment of viral encephalitis. Methods Sixty patients with viral encephalitis were randomly divided into ganciclovir-naloxone group (treatment group) and ganciclovir group (control group), 30 cases in each group. Both groups were given intravenous Two groups of patients treated for observation. Results The ganciclovir of naloxone treatment group was significantly shorter than that of ganciclovir group in treating viral encephalitis, headache, vomiting, convulsion and consciousness recovery (P <0.01). Conclusion Ganciclovir combined with naloxone in the treatment of viral encephalitis has obvious curative effect, rapid effect, good safety and few adverse reactions, which deserves clinical promotion.