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幽门螺杆菌（Ｈｐ）与胃炎、消化性溃疡和胃癌的发生密切相关，人群感染率高达３０％～９０％。Ｈｐ感染者经抗菌药物治愈后的天然免疫力似不足以防止再感染，患者常在１年内复发。有文献报道以重组Ｈｐ尿素酶免疫小鼠可预防猫螺杆菌再感染。本文选用与人类免疫系统更相近的恒
Helicobacter pylori (Hp) and gastritis, peptic ulcer and gastric cancer are closely related to the population infection rate as high as 30% to 90%. The natural immunity of Hp infected patients after being cured by antimicrobial drugs may not be enough to prevent re-infection. Patients often relapse within one year. It has been reported in the literature to recombinant Hp urease mice can prevent cat rein reinfection. This article selects the human immune system is more similar to the constant