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天门冬酸转氨酶(AST)由两种同功酶组成:一种与细胞质成分有关(S-AST);另一种与线粒体有关(m-AST)。作者根据这两种同功酶的免疫学特性不同,用免疫吸附剂完全除去S-AST后,将剩余的AST活性定为血清m-AST活性。82名受检者血清m-AST活性平均值为1.0ku/ml;31例急性心肌梗塞患者血清m-AST水平均异常升高(大于5ku/ml)。梗塞发生后平均34.6±3.2小时,m-AST活性达到高峰值(65.7±9.8ku/ml),发病后第9日降至正常。梗塞后平均29.4±2.9小时(比m-AST早约5小时),t-AST(总AST)达
Aspartate aminotransferase (AST) is composed of two isozymes: one related to the cytoplasmic component (S-AST) and the other to mitochondria (m-AST). Based on the different immunological properties of the two isoenzymes, the authors removed the AST activity completely as serum m-AST activity after completely removing S-AST from the immunosorbent. The average serum m-AST activity of the 82 subjects was 1.0ku / ml. The serum m-AST level was abnormally elevated (greater than 5ku / ml) in 31 patients with acute myocardial infarction. After infarction occurred on average 34.6 ± 3.2 hours, m-AST activity reached its peak (65.7 ± 9.8ku / ml), and dropped to normal on the 9th day after onset. Mean post-infarction 29.4 ± 2.9 hours (approximately 5 hours earlier than m-AST), t-AST (total AST)