论文部分内容阅读
目的:探讨苯那普利治疗肾移植术后高血压的有效性和安全性。方法:以环孢素A为基础免疫抑制治疗的肾移植患者26例,测定血肌酐、24 h尿蛋白定量、血红蛋白、肝功能、血脂及血压的基础值和术后应用苯那普利6个月后的改变值。结果:苯那普利治疗后,患者收缩压及舒张压较基础值均有所下降,均达到目标值范围,差异有统计学意义(P<0.05);患者血红蛋白,尿蛋白较基础值下降,差异有统计学意义(P<0.05)。结论:苯那普利可有效控制肾移植术后高血压,并有降压以外的优势。
Objective: To investigate the efficacy and safety of benazepril in the treatment of hypertension after renal transplantation. Methods: Twenty-six renal transplant recipients were treated with cyclosporine A based on immunosuppression. The basal values of serum creatinine, 24 h urinary protein, hemoglobin, liver function, blood lipid and blood pressure were determined. Six benazepril Changes after month. Results: After benazepril treatment, systolic blood pressure and diastolic blood pressure decreased compared with the baseline values, reaching the target value range, the difference was statistically significant (P <0.05); patients with hemoglobin, urinary protein than the baseline value decreased, The difference was statistically significant (P <0.05). Conclusion: Benazepril is effective in controlling post-renal hypertension and has advantages beyond blood pressure.