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利多卡因作为抗心律不齐的药物已广泛地使用于临床。利多卡因是抗痉挛效果较好的药物。重度癫痫病人包括大发作、小发作、杰克森氏癫痫等各种症状,在使用利多卡因静脉注射后均收到了显著疗效。1958年 Tarener 和 Bain 曾对三例重度癫痫病人,用利多卡因静脉注射与生理盐水静脉注射两者进行双盲比较实验,明确了本剂对延长重症病人中止发作时间有显著的作用。使用利多卡因的优点是:(1)认为有速效性。(2)不致使意识水平低下。(3)如果慎重使用,其副作用较少。(4)能够持续静脉点滴。(5)使用安定和其它抗痉挛药物疗效不佳及病人合并有慢性呼吸系疾病不能使用安定时,可使用利多卡因疗法。
Lidocaine as anti-arrhythmic drugs have been widely used in clinical. Lidocaine is a good anti-spasm drugs. Patients with severe epilepsy, including major episodes, small seizures, and Jackson’s epilepsy, all received significant results after intravenous injection of lidocaine. Tarener and Bain in 1958 had three cases of severe epilepsy patients, intravenous injection of lidocaine and saline intravenous double-blind comparison of both experiments, clear the agent to extend the duration of severe disease in patients with termination of a significant role. The advantages of using lidocaine are: (1) quick-acting. (2) Do not make the level of consciousness low. (3) If used with caution, its side effects are less. (4) to continuous intravenous drip. (5) Lidocaine therapy may be used when the use of diazepam and other anti-spastic drugs is ineffective and patients with chronic respiratory diseases may not be able to use diazepam.