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目的探究氯吡格雷联合阿司匹林在急性轻度脑梗死治疗中的临床治疗效果。方法 84例急性轻度脑梗死患者,以患者的病情为根据将患者分为对照组(38例)和实验组(46例)。对照组患者采用阿司匹林治疗,实验组患者采用氯吡格雷联合阿司匹林治疗。比较两组患者的临床治疗和不良反应发生情况。结果治疗14 d后,实验组患者治疗有效45例,有效率为97.8%;对照组患者治疗有效31例,有效率为81.6%,实验组患者治疗有效率高于对照组,差异具有统计学意义(P<0.05);治疗后,两组患者美国国立卫生研究院卒中量表(NIHSS)评分低于治疗前,差异具有统计学意义(P<0.05),但两组患者NIHSS评分比较差异无统计学意义(P>0.05)。两组患者不良反应均较轻。结论通过联合氯吡格雷与阿司匹林对急性轻度脑梗死患者实施临床治疗,阻止了卒中的发展,安全系数更高,提升了预后质量。
Objective To investigate the clinical effect of clopidogrel combined with aspirin in the treatment of acute mild cerebral infarction. Methods Eighty-four patients with acute mild cerebral infarction were divided into control group (n = 38) and experimental group (n = 46) based on the patient’s condition. Patients in the control group were treated with aspirin, and patients in the experimental group were treated with clopidogrel plus aspirin. The clinical treatment and adverse reactions of the two groups were compared. Results After 14 days of treatment, 45 cases were treated effectively in the experimental group, with an effective rate of 97.8%. In the control group, 31 cases were effectively treated and the effective rate was 81.6%. The treatment efficiency in the experimental group was higher than that in the control group, with statistically significant difference (P <0.05). After treatment, NIHSS scores of the two groups were lower than those before treatment (P <0.05), but NIHSS scores of the two groups had no statistical difference Significance (P> 0.05). Adverse reactions were mild in both groups. Conclusion Clopidogrel and aspirin in patients with acute mild cerebral infarction clinical treatment, preventing the development of stroke, higher safety factor, improve the quality of prognosis.