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七十年代是免疫学研究取得丰硕成果的10年。免疫应答机制中的细胞间协同作用及其遗传调控得到了阐明。免疫球蛋白基因的研究有飞速的进展。至少八十年代前期免疫学研究的一大方向,是从生物化学和分子生物学角度研究免疫应答机制,并将获得的知识应用于临床免疫学。但是淋巴细胞的多样性是研究的一个障碍。肿瘤性淋巴细胞系、骨髓瘤细胞或淋巴细胞白血病细胞是自然形成的单克隆细胞群,因而是克服淋巴细胞多样性的极好材料。现在人们在更积极地试图建立 T 细胞或 B 细胞的单克隆细胞株。
Seventies is a decade of successful immunology research. The cell-cell synergy and its genetic regulation in the immune response mechanism are elucidated. The progress of immunoglobulin gene research is rapid. At least one of the major directions of immunology research in the early 1980s is to study immune response mechanisms from the perspective of biochemistry and molecular biology and to apply the acquired knowledge to clinical immunology. However, the diversity of lymphocytes is a barrier to research. Tumor lymphoid lines, myeloma cells or lymphocytic leukemia cells are naturally occurring populations of monoclonal colonies and are therefore excellent materials for overcoming lymphocyte diversity. Now people are more aggressively trying to create T cell or B cell monoclonal cell lines.