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嗜酸粒细胞来自造血干细胞,造血干细胞起源于胚胎早期卵黄囊壁上的血岛,在胚胎期的肝、脾是造血干细胞形成嗜酸粒细胞的微环境,而作为中枢淋巴器官的胸腺,则是T淋巴细胞形成和培育的微环境,胎儿胸腺中却有大量嗜酸粒细胞出现,胸腺是否也是嗜酸粒细胞培育的微环境,报道甚少。本文为了探索该问题,对12～40周的胎儿胸腺组织发生与嗜酸粒细胞进行了形态学观察。认为嗜酸粒细胞最早出现于胎儿12周的胸腺。
Eosinophils from hematopoietic stem cells, hematopoietic stem cells originated in the early embryo yolk wall blood island, in the embryonic liver, spleen hematopoietic stem cells to form eosinophils microenvironment, and as the central lymphoid organ thymus, then Is the formation and cultivation of T lymphocytes in the microenvironment, there is a large number of fetal thymus eosinophils appear, whether the thymus is eosinophil culture microenvironment, rarely reported. In order to explore this issue, we studied the morphological changes of fetal thymus and eosinophils from 12 to 40 weeks. Eosinophils are thought to first appear in the thymus of the fetus at 12 weeks.