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8例21～26岁服甾体激素避孕药的妇女在服药第10天或第28天分别服用不同剂量的安定(0.07,0.14和0.28mg/kg),以观察安定对精神运动(以轨迹测验SCT 为指标)和识知编码试验(以数字符号测验DSS为指标)的有害影响并以服用相同剂量安定的年轻配对男性作比较,实验设计采用双盲拉丁区组。结果发现,服用避孕药妇女和年轻男子在服用高剂量安定(0.28mg/kg)后均表现明显的SCT 和DSS 损伤,服用避孕药妇女口服中等剂量和低剂量安定时不表现明显的SCT 和DSS 损伤,但年轻男子服用中等量安定(0.14mg/kg)者在服药20min 后也出现损伤。通常,服用避孕药妇
Eight women aged 21 to 26 years who took steroid hormonal contraceptives took diazepam (0.07, 0.14 and 0.28 mg / kg) at different dosages on the 10th or 28th day of medication to observe the effects of diazepam on psychomotor SCT) and cognitive coding trials (DSS as an index) were compared and dosed with young matched males of the same dose and stability, using a double-blind Latin group for the experimental design. The results showed that women taking contraceptives and young men showed obvious SCT and DSS damage after taking high-dose diazepam (0.28mg / kg). Women taking oral contraceptives did not show obvious SCT and DSS when taking oral medium and low doses of diazepam However, younger men taking moderate doses of diazepam (0.14 mg / kg) also experienced damage 20 min after taking the drug. In general, take contraceptives