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为了解中国汉族Ｃ１Ｒ的遗传多态性，采用聚丙烯酰胺等电聚焦结合免疫斑点转移的方法检测了３个城市中无亲缘关系的３１７名中国汉族献血员（吉林市１０５人，成都市１１１人，广州市１０１人）的Ｃ１Ｒ表现型。结果显示：这三个汉族群体均有Ｃ１Ｒ＊１、Ｃ１Ｒ＊２和Ｃ１Ｒ＊５等三个常见等位基因。其频率分别为：吉林，Ｃ１Ｒ＊１＝０．５３８１，Ｃ１Ｒ＊２＝０．２６１９，Ｃ１Ｒ＊５＝０．１７１４；成都，Ｃ１Ｒ＊１＝０．５６７６，Ｃ１Ｒ＊２＝０．３４２３，Ｃ１Ｒ＊５＝０．０８５６；广州，Ｃ１Ｒ＊１＝０．５２４８，Ｃ１Ｒ＊２＝０．３６６３，Ｃ１Ｒ＊５＝０．１０８９。同时还发现了Ｃ１Ｒ＊６、Ｃ１Ｒ＊７、Ｃ１Ｒ＊８等三个稀有基因。由此可见，在中国汉族人群中，Ｃ１Ｒ＊２的频率从北向南逐渐上升。说明可能存在地理渐变群（Ｃｌｉｎｅ）。在中国汉族，其累积杂合度达６１．５１％，提示该系统在人类学和法医学中具有良好的应用前景
In order to understand the genetic polymorphism of C1R in Han nationality of China, 317 unrelated Han Chinese blood donors (105 in Jilin City, 111 in Chengdu City) were detected by polyacrylamide isoelectric focusing combined with immunoblotting. , Guangzhou 101) C1R phenotype. The results showed that there are three common alleles of C1R * 1, C1R * 2 and C1R * 5 in these three Han nationality populations. The frequencies were: Jilin, C1R * 1 = 0.5381, C1R * 2 = 0.2619, C1R * 5 = 0.1714; Chengdu, C1R * 1 = 0.5676, C1R * 2 = 0.3423, C1R * 5 = 0.0856; Guangzhou, C1R * 1 = 0.5248, C1R * 2 = 0.3663, C1R * 5 = 0.1089. Also found three rare genes C1R * 6, C1R * 7, C1R * 8. Thus, in the Han Chinese population, the frequency of C1R * 2 gradually increases from north to south. Explain the possible existence of Cline. In Han Chinese, the cumulative heterozygosity reached 61.51%, suggesting that the system has a good application prospect in anthropology and forensic science