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观察了冠心病（ＣＨＤ）、恶性实体瘤（ＭＰＴ）病人和正常对照（ＮＣ）者血浆脂蛋白（ａ）（Ｌｐ（ａ））、甘油三酯（ＴＧ）、总胆固醇（ＴＣ）、载脂蛋白Ａ－Ｉ（ＡｐｏＡ－Ｉ）和载脂蛋白Ｂ（ＡｐｏＢ）的水平。结果显示，ＣＨＤ组（１９例）Ｌｐ（ａ）水平（ｍｇ／ｄｌ）为２２．０７±１２．６５，ＭＰＴ组（２６例）为２３．２８±１１．８０，两者均显著高于ＮＣ组（４０例）的１６．６５±７．６１（分别为Ｐ＜０．０５，Ｐ＜０．０１）。ＣＨＤ组ＴＧ、ＴＣ和ＡｐｏＢ均高于ＮＣ组者，ＡｐｏＡ－Ｉ则低于ＮＣ组者。ＭＰＴ组ＴＧ、ＴＣ、ＡｐｏＡ－Ｉ和ＡｐｏＢ均低于ＮＣ组者。作者结合文献分析认为，Ｌｐ（ａ）在ＣＨＤ的发生发展以及ＭＰＴ的增殖与转移中发挥一定的作用。
The levels of plasma lipoprotein (a), triglyceride (TG), total cholesterol (TC), serum lipids in patients with coronary heart disease (CHD), malignant solid tumor (MPT) and normal controls (NC) Protein A-I (ApoA-I) and Apolipoprotein B (ApoB) levels. The results showed that the level of Lp (a) was 22.07 ± 12.65 in CHD group (19 cases) and 23.28 ± 11.80 in MPT group (26 cases), both of which were significantly higher than NC Group (40 cases) of 16.65 ± 7.61 (P <0.05, P <0.01, respectively). TG, TC and ApoB in CHD group were higher than NC group, ApoA-I was lower than NC group. TG, TC, ApoA-I and ApoB in MPT group were lower than those in NC group. The author combined with the literature analysis that, Lp (a) plays a role in the occurrence and development of CHD and the proliferation and metastasis of MPT.