论文部分内容阅读
目的探讨提高抗菌药物治疗应用前临床病原微生物标本送检率的有效措施,了解其干预效果。方法采取制定与实施微生物标本采集与运送标准操作规程、培训、量化考核等综合干预措施,规范临床病原微生物标本送检,比较干预前、后住院患者治疗性应用抗菌药物前临床病原微生物标本送检率。结果干预后,医院抗菌药物治疗应用前、限制级和特殊级抗菌药物治疗应用前病原微生物标本送检率逐年提高,2012年病原微生物标本送检率由2011年的49.25%、46.87%和80.88%上升至63.63%、66.21%和90.33%;2013年提升至73.39%、83.41%和95.07%,2013年和2012年分别与2011年比较、2013年与2012年比较差异均有统计学意义(P<0.01);全部临床科室病原学送检率较干预前均有明显增高,达到了原卫生部要求。结论综合干预措施能提高临床病原微生物标本送检率。
Objective To explore the effective measures to improve the rate of clinical pathogenic microorganisms before antimicrobial treatment, and to understand the intervention effect. Methods The comprehensive interventions, such as standard operating procedures for the collection and delivery of microbiological specimens, training, quantitative assessment and so on, were formulated and implemented. The samples of clinical pathogenic microorganisms were submitted for inspection. Pre-clinical and post-antimicrobial agents were collected before and after intervention rate. Results Before the application of antimicrobial therapy in hospitals, the rate of detection of pre-pathogenic microbiological samples before the application of antimicrobial therapy of restricted grade and special grade increased year by year. In 2012, the rate of detection of pathogenic micro-organisms was 49.25%, 46.87% and 80.88% respectively in 2011, Increased to 63.63%, 66.21% and 90.33% respectively; in 2013 it increased to 73.39%, 83.41% and 95.07% respectively. Compared with 2011 in 2013 and 2012, the difference between 2013 and 2012 was statistically significant (P < 0.01). The etiological rates of all clinical departments were significantly higher than those before the intervention, reaching the requirements of the former Ministry of Health. Conclusion Comprehensive interventions can improve the delivery rate of clinical pathogenic microorganisms.