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从传统的观念来看药物的毒性,主要是指药物的药理作用强烈,到一定剂量就会引起吐、泻、出血、皮疹、脏器坏死、昏迷、抽搐,甚则死亡,以及孕妇堕胎等等急性中毒反应。历代本草著作将有这些反应的药物都标以“大毒”、“小毒”字样。然而近年来对一小部分中草药,包括一些以往认为无毒的药物还可能具有的另一类毒性——诱变作用和致畸作用,也开始被人们所重视。
The traditional concept of drug toxicity, mainly refers to the drug’s strong pharmacological effects, to a certain dose can cause spit, diarrhea, bleeding, rash, organ necrosis, coma, convulsions, and even death, as well as pregnant women abortion, etc. Acute poisoning reaction. Herbal writings in ancient times have labeled these drugs as “great poisons” and “small poisons.” However, in recent years, a relatively small number of Chinese herbal medicines, including some of the previously considered non-toxic drugs, may also have another type of toxicity-mutagenicity and teratogenicity, which have also begun to receive attention.