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对40例甲亢病人单用心得安作术前准备,并在针刺麻醉下施行甲状腺次全切除术,以观察病人在神志清醒状态手术时心得安的疗效。口服给药,每6小时一次,首剂10毫克,逐日加大剂量,每日用药量40～800毫克。待基础代谢降至正常水平即行手术,所有病例均告成功。术后心得安剂量逐日递减,以防止甲亢病象的“反跳”。本组无一例出现甲亢危象”,亦未出现心得安所致的心动过缓、传导阻滞等不良反应。
Forty patients with hyperthyroidism were used alone for the safety of preoperative preparation and anesthesia in the implementation of subtotal thyroidectomy in order to observe the patient in the conscious state of surgery when the effect of peace of mind. Oral administration, once every 6 hours, the first dose of 10 mg, increasing daily dose of 40 to 800 mg daily dose. When the basal metabolism is reduced to normal level, surgery is performed, and all cases are successful. Postoperative propranolol daily dose decreased, to prevent the phenomenon of hyperthyroidism “rebound.” No case of hyperthyroidism crisis in this group, "nor did the safety of the heart caused by bradycardia, conduction block and other adverse reactions.