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接触毒性物质诸如锰,一氧化碳,和双硫碳化物可产生震颤麻痹症。作者报告一例慢性吸入四氯化碳(CCl_4)后发生震颤麻痹综合症。四氯化碳约20公斤通过一个缺陷的蒸发器慢慢漏出使病人被污染,病人接触四氯化碳蒸气约三个多月,其后出现迅速进行性的运动障碍,强直,和静止性震颤。震颤麻痹症在数月内变得严重但是没有其他神经病灶体征和对左旋多巴有反应。没有脑炎、头部损伤、或服药历史,亦无震颤麻痹症家族史。生化及代谢性检查阴性,亦无肝病及肾病。四氯化碳中毒的神经病征象包括脑脊髓病、脑出血、小脑变性、周围细胞病及视神经萎缩。以四氯化
Poison paralysis can result from exposure to toxic substances such as manganese, carbon monoxide, and disulfide carbides. The authors report a case of Parkinsonism syndrome after chronic inhalation of carbon tetrachloride (CCl 4). Approximately 20 kg of carbon tetrachloride leaks through a defective evaporator and leaves the patient contaminated. Patients exposed to carbon tetrachloride vapor for about three months, followed by rapid progressive dyskinesia, ankylosis, and rest tremor . Parkinsonism became severe within a few months but no other signs of neuropathy and response to levodopa. No encephalitis, head injury, or history of medication, and no family history of Parkinsonism. Biochemical and metabolic tests were negative, nor liver disease and kidney disease. Neurological symptoms of carbon tetrachloride poisoning include cerebrospinal myelopathy, cerebral hemorrhage, cerebellar degeneration, peripheral cytopathic and optic atrophy. To four chloride