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用与乙酰胆碱受体（ＡｃｈＲ）特异性结合的α－银环蛇毒素（α－ＢＧＴ）包被酶标板提纯肌肉粗提液中的ＡｃｈＲ作为抗原，按ＡＢＣ－ＥＬＩＳＡ间接法检测了５１例正常对照组，５２例临床对照组及９６例（１１０次）重症肌无力（ＭＧ）病人血清中的ＩｇＧ乙酰胆碱受体抗体（ＩｇＧ－ＡｃｈＲａｂ）。结果发现ＩｇＧ－ＡｃｈＲａｂ在ＭＧ组有３９例阳性（４４次）（４０．６３％）。临床对照组４例阳性（７．６９％）。正常对照组２例阳性，统计学处理发现ＭＧ组与其它组差异均有显著性（Ｐ＜０．０５），而临床对照组与正常对照组差异无显著性（Ｐ＞０．０５）。
The AchR in muscle crude extract was purified with a-bungarotoxin (α-BGT) coated with AchR and used as antigen to detect 51 normal cases by ABC-ELISA indirect method Control group, 52 cases of clinical control group and 96 cases (110 cases) of myasthenia gravis (MG) serum in patients with IgG acetylcholine receptor antibody (IgG-AchRab). The results showed IgG-AchRab in the MG group, 39 cases were positive (44 times) (40.63%). 4 cases of clinical control group positive (7.69%). The positive control group was positive in 2 cases. There was significant difference between the MG group and other groups (P <0.05), but there was no significant difference between the control group and the normal control group (P> 0.05).