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目的探讨不同化疗方案治疗子宫颈鳞癌复发患者效果,为临床选择提供意见和参考。方法选择1999年5月-2009年12月在我院采用化疗治疗子宫颈鳞癌复发患者105例进行回顾性研究。采用SPSS13.0统计分析软件进行分析。结果研究人群子宫颈鳞癌复发患者复发后化疗方案为两种采用紫杉醇+铂类为49例,占46.67%,采用其他治疗方案的为56例,占53.33%。随访1年,进行单因素Log-Rank分析发现生存率与复发部位、肿瘤分级、治疗方案和化疗是否有效有关。经COX多因素分析发现采用化疗治疗子宫颈鳞癌复发患者预后影响因素为化疗方案和化疗方案是否有效。结论采用化疗治疗子宫颈鳞癌复发患者有着较好的效果且影响因素较多。
Objective To investigate the effect of different chemotherapy regimens in patients with recurrent cervical squamous cell carcinoma and to provide suggestions and references for clinical choice. Methods From May 1999 to December 2009 in our hospital using chemotherapy in the treatment of 105 cases of recurrent cervical squamous cell carcinoma were retrospectively studied. Using SPSS13.0 statistical analysis software for analysis. Results Study population recurrence after recurrent cervical squamous cell carcinoma chemotherapy regimen for the two with paclitaxel + platinum in 49 cases, accounting for 46.67%, with other treatment options for 56 cases, accounting for 53.33%. Follow-up of 1 year, single-factor Log-Rank analysis found that survival rate and recurrence site, tumor grade, treatment and chemotherapy is effective. COX multivariate analysis found that the use of chemotherapy in the treatment of recurrent cervical squamous cell prognosis factors for chemotherapy and chemotherapy regimens are effective. Conclusion Chemotherapy for recurrent cervical squamous cell carcinoma patients has a good effect and more influencing factors.