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用放免法测定了５７例急性脑血管意外患者（脑梗塞３１例，脑出血２６例，其中６例出现明显心肌缺血，３例出现急性心肌梗塞）急性期及恢复期血浆内皮素和心钠素的变化，发现心钠素在脑出血时升高，在脑梗塞时下降。内皮素在脑出血、脑梗塞时均升高，脑出血又高于脑梗塞组（Ｐ＜０．０５）；脑出血组中无心肌缺血者与并发心肌缺血者比较Ｐ＜０．０５，与急性心肌梗者比较Ｐ＜０．０１，认为内皮素、心钠素在脑血管意外及脑心综合征的发病过程中起着重要作用，可作为预测并发症的观察指标
57 patients with acute cerebrovascular accident (cerebral infarction in 31 cases, cerebral hemorrhage in 26 cases, 6 cases of significant myocardial ischemia, 3 cases of acute myocardial infarction) were determined by radioimmunoassay in acute and convalescent phase of plasma endothelin and sodium Changes in the hormone found that atrial natriuretic sodium increased in cerebral hemorrhage, decreased in cerebral infarction. Endothelin in cerebral hemorrhage, cerebral infarction were elevated, cerebral hemorrhage was higher than that of cerebral infarction group (P <0.05); cerebral hemorrhage group without myocardial ischemia compared with those with myocardial ischemia P <0.05 , P <0.01 compared with acute myocardial infarction, that endothelin, atrial natriuretic peptide in cerebrovascular accident and brain syndrome play an important role in the pathogenesis, can be used as a predictor of complications