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经皮冠状动脉药物洗脱支架植入术后有两种常见的并发症，一是支架内血栓形成，二是支架内再狭窄。降低这两种并发症发生率的重要方法是双联抗血小板药物治疗，但目前关于双联抗血小板药物治疗的最佳持续时间仍然存在争议。通过回顾近年来的大型临床试验及荟萃分析等相关文献，为临床医生在双联抗血小板药物治疗最佳持续时间方面提供一些可行性建议。“,”Drug-eluting stents implantation has two common complications:stent thrombosis and angiographic restenosis .Dual anti-platelet therapy ( DAPT) is one of the most important methods to prevent complications ,and the duration of DAPT is controversial at present . This review aimed to identify related randomized clinical trials and meta-analyses to provide some feasible suggestions to clinicians of the op-timal duration .