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一氧化氮 ( Nitric oxide,NO)是一种难溶于水的脂溶性气体。它在体内扮演着生理和病理的双重角色。小剂量 NO有着重要的信息传递作用。在神经系统中具有类似神经递质的信息传递功能 ;在免疫系统中具有杀灭肿瘤细胞、细菌、寄生虫和病毒的作用 ;在心血管系统中具有扩张血管 ,抑制血小板聚集与粘附 ,调节血流和血压的功能。但大剂量 NO,又可产生细胞毒性 ,导致组织细胞损伤 ,是肝组织损伤的重要介导因子
Nitric oxide (NO) is a poorly water-soluble, fat-soluble gas. It plays a dual role of physiology and pathology in the body. Small doses of NO have an important message passing function. In the nervous system has a similar neurotransmitter information transmission function; in the immune system with the role of killing tumor cells, bacteria, parasites and viruses; in the cardiovascular system with dilation of blood vessels, inhibition of platelet aggregation and adhesion, regulate blood Flow and blood pressure function. However, high-dose NO, but also produce cytotoxicity, resulting in tissue injury, is an important mediator of liver tissue damage